Design and Selection Parameters to Accelerate the Discovery of Novel Central Nervous System Positron Emission Tomography (PET) Ligands and Their Application in the Development of a Novel Phosphodiesterase 2A PET Ligand-Reference-Cited by-同舟云学术

Design and Selection Parameters to Accelerate the Discovery of Novel Central Nervous System Positron Emission Tomography (PET) Ligands and Their Application in the Development of a Novel Phosphodiesterase 2A PET Ligand

Published:2013-05-28 Issue:11 Volume:56 Page:4568-4579
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhang Lei¹,Villalobos Anabella¹,Beck Elizabeth M.¹,Bocan Thomas²,Chappie Thomas A.¹,Chen Laigao²,Grimwood Sarah³,Heck Steven D.⁴,Helal Christopher J.⁵,Hou Xinjun¹,Humphrey John M.⁵,Lu Jiemin⁵,Skaddan Marc B.²,McCarthy Timothy J.²,Verhoest Patrick R.¹,Wager Travis T.¹,Zasadny Kenneth²

Affiliation:

1. Neuroscience Medicinal Chemistry, Pfizer Inc., Cambridge, Massachusetts 02139, United States

2. BioImaging Center, Precision Medicine, Pfizer Inc., Groton, Connecticut 06340, United States

3. Neuroscience Research Unit, Pfizer Inc., Cambridge, Massachusetts 02139, United States

4. Data Analytical Group, Groton Center of Chemistry, Groton, Connecticut 06340, United States

5. Neuroscience Medicinal Chemistry, Pfizer Inc., Groton, Connecticut 06340, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm400312y

Reference39 articles.

1. Molecular Imaging with PET

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