Experimental, Thermodynamic, and Molecular Modeling Evaluation of Amorphous Simvastatin-Poly(vinylpyrrolidone) Solid Dispersions
Author:
Affiliation:
1. Department of Pharmaceutical Technology, School of Pharmacy, Aristotle University of Thessaloniki, Thessaloniki 54124, Greece
2. Ecoresources P.C., 15-17 Giannitson-Santaroza Str., Thessaloniki 54627, Greece
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Pharmaceutical Science,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.0c00413
Reference73 articles.
1. Structural insight into the physical stability of amorphous Simvastatin dispersed in pHPMA: Enhanced dynamics and local clustering as evidenced by solid-state NMR and Raman spectroscopy
2. Relative Lipophilicities, Solubilities, and Structure–Pharmacological Considerations of 3-Hydroxy-3-Methylglutaryl-Coenzyme A (HMG-CoA) Reductase Inhibitors Pravastatin, Lovastatin, Mevastatin, and Simvastatin
3. Preparation, Characterization, and Dissolution Behavior of a Solid Dispersion of Simvastatin with Polyethylene Glycol 4000 and Polyvinylpyrrolidone K30
4. Preparation and characterization of solid dispersion of simvastatin
5. Statins in dermatology
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