Hydrogen Bonding Principle-Based Molecular Design of a Polymer Excipient and Impacts on Hydrophobic Drug Properties: Molecular Simulation and Experiment-Reference-Cited by-同舟云学术

Hydrogen Bonding Principle-Based Molecular Design of a Polymer Excipient and Impacts on Hydrophobic Drug Properties: Molecular Simulation and Experiment

Published:2023-03-03 Issue:4 Volume:24 Page:1675-1688
ISSN:1525-7797
Container-title:Biomacromolecules
language:en
Short-container-title:Biomacromolecules

Author:

Zhang Sidian¹,Wang Tao²^ORCID,Xue Jiajia¹,Xu Haiyan²^ORCID,Wu Sizhu¹^ORCID

Affiliation:

1. State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology, Beijing 100029, P. R. China

2. Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, P. R. China

Funder

Central University Basic Research Fund of China

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Materials Chemistry,Polymers and Plastics,Biomaterials,Bioengineering

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.biomac.2c01473

Reference48 articles.

1. Advances in Polymer Design for Enhancing Oral Drug Solubility and Delivery

2. Polymeric Amorphous Solid Dispersions: A Review of Amorphization, Crystallization, Stabilization, Solid-State Characterization, and Aqueous Solubilization of Biopharmaceutical Classification System Class II Drugs

3. Formulation design for poorly water-soluble drugs based on biopharmaceutics classification system: Basic approaches and practical applications

4. Solid dispersions of telaprevir with improved solubility prepared by co-milling: formulation, physicochemical characterization, and cytotoxicity evaluation

5. Rheology of Cellulose Ether Excipients Designed for Hot Melt Extrusion

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