Increasing the Potential of the Auristatin Cancer-Drug Family by Shifting the Conformational Equilibrium
Author:
Affiliation:
1. Department of Chemistry, University of Helsinki, P.O. Box 55, FI-00014 Helsinki, Finland
2. Helsinki Institute of Sustainability Science, HELSUS, FI-00014 Helsinki, Finland
Funder
Academy of Finland
Jane ja Aatos Erkon S????ti??
Helsingin Yliopisto
Waldemar von Frenckells stiftelse
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Pharmaceutical Science,Molecular Medicine
Link
http://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.9b00437
Reference92 articles.
1. Dolastatin 10, a powerful cytostatic peptide derived from a marine animal
2. Arming antibodies: prospects and challenges for immunoconjugates
3. Enhanced Activity of Monomethylauristatin F through Monoclonal Antibody Delivery: Effects of Linker Technology on Efficacy and Toxicity
4. The discovery and development of brentuximab vedotin for use in relapsed Hodgkin lymphoma and systemic anaplastic large cell lymphoma
5. Tubulin Inhibitor-Based Antibody-Drug Conjugates for Cancer Therapy
Cited by 8 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Precision Drug Delivery to Tackle Antibiotic Resistance;Advances in Medical Diagnosis, Treatment, and Care;2024-03-15
2. Efficacy of depatuxizumab mafodotin (ABT-414) in preclinical models of head and neck cancer;Carcinogenesis;2024-02-20
3. Design, synthesis of auristatins-glucuronide conjugates targeting the β-glucuronidase in tumor microenvironment;Bioorganic & Medicinal Chemistry Letters;2023-10
4. Approved Protein Therapeutics and Their Biochemical Targets;Protein-based Therapeutics;2023
5. Antibody-drug conjugates for lymphoma patients: preclinical and clinical evidences;Exploration of Targeted Anti-tumor Therapy;2022-12-26
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3