Salt Disproportionation in the Solid State: Role of Solubility and Counterion Volatility-Reference-Cited by-同舟云学术

Salt Disproportionation in the Solid State: Role of Solubility and Counterion Volatility

Published:2016-11-02 Issue:12 Volume:13 Page:4141-4151
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Thakral Naveen K.¹²,Behme Robert J.¹,Aburub Aktham¹,Peterson Jeffrey A.¹,Woods Timothy A.¹,Diseroad Benjamin A.¹,Suryanarayanan Raj²,Stephenson Gregory A.¹

Affiliation:

1. Lilly Corporate Center, Eli Lilly and Company, Indianapolis, Indiana 46285, United States

2. Department of Pharmaceutics, College of Pharmacy, University of Minnesota, Minneapolis, Minnesota 55455, United States

Funder

Eli Lilly and Company

William and Mildred Peters Endowment Fund

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.6b00745

Reference31 articles.

1. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

2. FINDING SOLUTIONS

3. Salt formation to improve drug solubility

4. Salt form selection and characterization of LY333531 mesylate monohydrate

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