Development of new multicomponent crystals of the antifungal drug tioconazole and the assessment of their biopharmaceutical attributes-Reference-Cited by-同舟云学术

Development of new multicomponent crystals of the antifungal drug tioconazole and the assessment of their biopharmaceutical attributes

Published:2023 Issue:48 Volume:25 Page:6758-6776
ISSN:1466-8033
Container-title:CrystEngComm
language:en
Short-container-title:CrystEngComm

Author:

Madhesiya Avinash¹^ORCID,Dash Sibananda G.¹²^ORCID,Gupta Princi¹,Akhir Abdul³^ORCID,Saxena Deepanshi³^ORCID,Maitra Rahul³^ORCID,Chopra Sidharth³,Thakur Tejender S.¹²^ORCID

Affiliation:

1. Biochemistry and Structural Biology Division, CSIR-Central Drug Research Institute, Lucknow 226 031, India

2. Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201 002, India

3. Molecular Microbiology and Immunology Division, CSIR-Central Drug Research Institute, Lucknow 226 031, India

Abstract

New multicomponent crystals of the antifungal drug tioconazole with improved solubility and dissolution rate were identified with the help of a rational coformer screening.

Funder

University Grants Commission

Council of Scientific and Industrial Research, India

Department of Science and Technology, Ministry of Science and Technology, India

Department of Biotechnology, Ministry of Science and Technology, India

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Materials Science,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CE/D3CE00948C

Reference29 articles.

1. Tioconazole

2. Antifungal Activity of Tioconazole (UK-20,349), a New Imidazole Derivative

3. Tioconazole, a New Broad-Spectrum Antifungal Agent: Preclinical Studies Related to Vaginal Candidiasis

4. An insight into the antifungal pipeline: selected new molecules and beyond

5. Antifungal agents and liver toxicity: a complex interaction