Phase Behavior of Drug-Hydroxypropyl Methylcellulose Amorphous Solid Dispersions Produced from Various Solvent Systems: Mechanistic Understanding of the Role of Polymer using Experimental and Theoretical Methods-Reference-Cited by-同舟云学术

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Phase Behavior of Drug-Hydroxypropyl Methylcellulose Amorphous Solid Dispersions Produced from Various Solvent Systems: Mechanistic Understanding of the Role of Polymer using Experimental and Theoretical Methods

Published:2018-06-06 Issue:8 Volume:15 Page:3236-3251
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Mugheirbi Naila A.¹,Mosquera-Giraldo Laura I.¹,Borca Carlos H.²,Slipchenko Lyudmila V.²^ORCID,Taylor Lynne S.¹^ORCID

Affiliation:

1. Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University, 575 Stadium Mall Drive, West Lafayette, Indiana 47907, United States

2. Department of Chemistry, College of Science, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907, United States

Funder

American Association of Pharmaceutical Scientists

U.S. Food and Drug Administration

Pharmaceutical Research and Manufacturers of America Foundation

National Institute for Pharmaceutical Technology and Education

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.8b00324

Reference42 articles.

1. Dissolution Rates of High Energy Sulfathiazole‐Povidone Coprecipitates II: Characterization of Form of Drug Controlling Its Dissolution Rate via Solubility Studies

2. Effects of Polymer Type and Storage Relative Humidity on the Kinetics of Felodipine Crystallization from Amorphous Solid Dispersions

3. Amorphous Solid Dispersions of Sulfonamide/Soluplus® and Sulfonamide/PVP Prepared by Ball Milling

4. Solubilities of Crystalline Drugs in Polymers: An Improved Analytical Method and Comparison of Solubilities of Indomethacin and Nifedipine in PVP, PVP/VA, and PVAc

5. Solid dispersion of poorly water‐soluble drugs: Early promises, subsequent problems, and recent breakthroughs

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