Harnessing Bile for Drug Absorption through Rational Excipient Selection-Reference-Cited by-同舟云学术

Harnessing Bile for Drug Absorption through Rational Excipient Selection

Published:2023-07-05 Issue:8 Volume:20 Page:3864-3875
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Schlauersbach Jonas¹^ORCID,Werthmüller Dominic²,Harlacher Cornelius²^ORCID,Galli Bruno²,Hanio Simon¹^ORCID,Lenz Bettina¹^ORCID,Endres Sebastian³,Pöppler Ann-Christin³^ORCID,Scherf-Clavel Oliver¹,Meinel Lorenz¹⁴^ORCID

Affiliation:

1. Institute for Pharmacy and Food Chemistry, University of Wuerzburg, Am Hubland, DE-97074 Wuerzburg, Germany

2. Novartis Pharma AG, Lichtstrasse 35, CH-4056 Basel, Switzerland

3. Institute of Organic Chemistry, University of Wuerzburg, Am Hubland, DE-97074 Wuerzburg, Germany

4. Helmholtz Institute for RNA-based Infection Biology (HIRI), Josef-Schneider-Strasse 2/D15, DE-97080 Wuerzburg, Germany

Funder

Novartis Pharma

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.2c01009

Reference65 articles.

1. Drug delivery strategies for poorly water-soluble drugs: the industrial perspective

2. Molecular inflation, attrition and the rule of five

3. An analysis of the attrition of drug candidates from four major pharmaceutical companies

4. Soluplus® as an effective absorption enhancer of poorly soluble drugs in vitro and in vivo

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