Conformational and Colloidal Stabilities of Human Immunoglobulin G Fc and Its Cyclized Variant: Independent and Compensatory Participation of Domains in Aggregation of Multidomain Proteins-Reference-Cited by-同舟云学术

Conformational and Colloidal Stabilities of Human Immunoglobulin G Fc and Its Cyclized Variant: Independent and Compensatory Participation of Domains in Aggregation of Multidomain Proteins

Published:2017-02-21 Issue:3 Volume:14 Page:699-711
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Yageta Seiki¹²,Shibuya Risa¹,Imamura Hiroshi²^ORCID,Honda Shinya¹²^ORCID

Affiliation:

1. Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8562, Japan

2. Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology, AIST Central 6, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8566, Japan

Funder

Ministry of Economy, Trade and Industry

Japan Agency for Medical Research and Development

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.6b00983

Reference63 articles.

1. Antibody Structure, Instability, and Formulation

2. The therapeutic monoclonal antibody market