Getting Smaller by Denaturation: Acid-Induced Compaction of Antibodies-Reference-Cited by-同舟云学术

Getting Smaller by Denaturation: Acid-Induced Compaction of Antibodies

Published:2023-04-24 Issue:16 Volume:14 Page:3898-3906
ISSN:1948-7185
Container-title:The Journal of Physical Chemistry Letters
language:en
Short-container-title:J. Phys. Chem. Lett.

Author:

Imamura Hiroshi¹²³^ORCID,Ooishi Ayako¹,Honda Shinya¹^ORCID

Affiliation:

1. Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1, Higashi, Tsukuba, Ibaraki 305-8566, Japan

2. Department of Applied Chemistry, College of Life Sciences, Ritsumeikan University, 1-1-1 Noji-Higashi, Kusatsu, Shiga 525-8577, Japan

3. Department of Bio-Science, Nagahama Institute of Bio-Science and Technology, 1266 Tamura, Nagahama, Shiga 526-0829, Japan

Funder

Japan Society for the Promotion of Science

Publisher

American Chemical Society (ACS)

Subject

General Materials Science,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jpclett.3c00258

Reference71 articles.

1. Introduction to Protein Science

2. Conformational Expansion of Tau in Condensates Promotes Irreversible Aggregation

3. Properties of protein unfolded states suggest broad selection for expanded conformational ensembles

4. Highly Aggregated Antibody Therapeutics Can Enhance the in Vitro Innate and Late-stage T-cell Immune Responses

5. Guidance for Industry: Immunogenicity Assessment for Therapeutic Protein Products. Food and Drug Administration, Center for Drug Evaluation and Research (CDER), Center for Biologics Evaluation and Research (CBER), 2014.

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