Glycan-Controlled Human PD-1 Variants Displaying Broad-Spectrum High Binding to PD-1 Ligands Potentiate T Cell

Author:

Ha Ji Yeon12,Chun Kwang-Jin3,Ko Sanghwan4,Lee Ho Won5,Hwang Ok Kyung5,Lim Chung Su5,Ha Kyungsoo5,Ko Byoung Joon6,Jung Sang Taek1247ORCID

Affiliation:

1. Department of Biomedical Sciences, Graduate School, Korea University, Seoul 02842, Republic of Korea

2. BK21 Graduate Program, Department of Biomedical Sciences, Korea University College of Medicine, Seoul 02842, Republic of Korea

3. Neuracle Science, Seoul 02841, Republic of Korea

4. Institute of Human Genetics, Korea University College of Medicine, Seoul 02842, Republic of Korea

5. New Drug Development Center, Osong Medical Innovation Foundation, 123, Cheongju, Chungcheongbuk-do 28160, Republic of Korea

6. School of Biopharmaceutical and Medical Sciences, Sungshin Women’s University, Seoul 02844, Republic of Korea

7. Biomedical Research Center, Korea University Anam Hospital, Seoul 02842, Republic of Korea

Funder

Korea Drug Development Fund

National Research Foundation of Korea

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

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