Comparison of the Expression Kinetics and Immunostimulatory Activity of Replicating mRNA, Nonreplicating mRNA, and pDNA after Intradermal Electroporation in Pigs-Reference-Cited by-同舟云学术

Comparison of the Expression Kinetics and Immunostimulatory Activity of Replicating mRNA, Nonreplicating mRNA, and pDNA after Intradermal Electroporation in Pigs

Published:2018-01-17 Issue:2 Volume:15 Page:377-384
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Leyman Bregje¹,Huysmans Hanne¹,Mc Cafferty Séan¹²,Combes Francis¹²,Cox Eric³,Devriendt Bert³,Sanders Niek N.¹²^ORCID

Affiliation:

1. Faculty of Veterinary Medicine, Department of Nutrition, Genetics, and Ethology, Laboratory for Gene Therapy, Ghent University, Heidestraat 19, 9820 Merelbeke, Belgium

2. Cancer Research Institute (CRIG), Ghent University, 9820 Merelbeke, Belgium

3. Faculty of Veterinary Medicine, Department of Virology, Parasitology, and Immunology, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium

Funder

Universiteit Gent

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.7b00722

Reference49 articles.

1. mRNA-based therapeutics — developing a new class of drugs