Restoring Endogenous Repair Mechanisms to Heal Chronic Wounds with a Multifunctional Wound Dressing

Author:

Atashgah Rahimeh B.12,Ghasemi Amir3,Raoufi Mohammad34,Abdollahifar Mohammad-Amin5,Zanganeh Steven6,Nejadnik Hossein7,Abdollahi Alieh2,Sharifi Shahriar8ORCID,Lea Baltazar1,Cuerva Miguel9,Akbarzadeh Mehdi10,Alvarez-Lorenzo Carmen11ORCID,Ostad Seyed Nasser2,Theus Andrea S.12ORCID,LaRock Doris L.13,LaRock Christopher N.13ORCID,Serpooshan Vahid121415ORCID,Sarrafi Rouzbeh16,Lee Ki-Bum17,Vali Hojatollah18,Schönherr Holger4ORCID,Gould Lisa1920,Taboada Pablo1ORCID,Mahmoudi Morteza82122ORCID

Affiliation:

1. Colloids and Polymers Physics Group, Particle Physics Department, Faculty of Physics and Health Research Institute of Santiago de Compostela (IDIS), Universidade de Santiago de Compostela, 15782, Santiago de Compostela, Spain

2. Department of Pharmaceutical Biomaterials and Medical Biomaterials Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran 14167-53955, Iran

3. Nanotechnology Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, 13169-43551, Iran

4. Physical Chemistry I, Department of Chemistry and Biology & Research Center of Micro and Nanochemistry and Engineering (Cμ), University of Siegen, Siegen 57076, Germany

5. Department of Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, 19395-4719, Iran

6. Department of Bioengineering, University of Massachusetts Dartmouth, Dartmouth, Massachusetts 02747, United States

7. Department of Radiology, University of Pennsylvania, Philladelphia, Pennsylvania 19104, United States

8. Precision Health Program, Michigan State University, East Lansing, Michigan 48824, United States

9. NANOMAG Group, Technological Research Institute (IIT), Physical Chemistry Department, University of Santiago de Compostela (USC), Santiago de Compostela 15782, Spain

10. Sadra Wound, Ostomy and Osteomyelitis Specialist Center, Tehran, Iran

11. R+D Pharma Group, Pharmacology, Pharmacy and Pharmaceutical Technology Department, Faculty of Pharmacy and Health Research Institute of Santiago de Compostela (IDIS), Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain

12. Wallace H. Coulter Department of Biomedical Engineering, Emory University School of Medicine and Georgia Institute of Technology, Atlanta, Georgia 30322, United States

13. Department of Microbiology and Immunology, Emory Antibiotic Resistance Center, Emory University School of Medicine, Atlanta, Georgia 30322, United States

14. Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia 30309, United States

15. Children’s Healthcare of Atlanta, Atlanta, Georgia 30322, United States

16. SciDerm, Natick, Massachusetts United States

17. Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854, United States

18. Department of Anatomy and Cell Biology and Facility for Electron Microscopy Research, McGill University, Montreal, Quebec H3A 0C3, Canada

19. Brown University School of Medicine, Providence, Rhode Island 02903, United States

20. South Shore Health System Center for Wound Healing, Weymouth, Massachusetts 02189, United States

21. Department of Anesthesiology, Brigham & Women’s Hospital, Harvard Medical School, Boston, Massachusetts 02115, United States

22. Mary Horrigan Connors Center for Women’s Health & Gender Biology, Brigham & Women’s Hospital, Harvard Medical School, Boston, Massachusetts 02115, United States

Funder

Brigham and Women's Hospital

European Regional Development Fund

Ministerio de Econom??a y Competitividad

Xunta de Galicia

National Science Foundation

Grupos de Referencia Competitiva

Agrupaci??n Estrat??gica de Materiales

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Reference74 articles.

1. Clinical challenges of chronic wounds: searching for an optimal animal model to recapitulate their complexity

2. A bioengineered living cell construct activates an acute wound healing response in venous leg ulcers

3. Wound repair and regeneration: Mechanisms, signaling, and translation

4. I-Corps: Multifunctional Patch for Chronic Wounds; National Science Foundation, 2019; award no. 1945779https://www.nsf.gov/awardsearch/showAward?AWD_ID=1945779 (accessed on 2021-07-07).

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