Quantitative Characterization of Clinically Relevant Drug-Metabolizing Enzymes and Transporters in Rat Liver and Intestinal Segments for Applications in PBPK Modeling-Reference-Cited by-同舟云学术

Quantitative Characterization of Clinically Relevant Drug-Metabolizing Enzymes and Transporters in Rat Liver and Intestinal Segments for Applications in PBPK Modeling

Published:2023-02-15 Issue:3 Volume:20 Page:1737-1749
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Sharma Sheena¹,Singh Dilip K.¹,Mettu Vijay S.¹,Yue Guihua¹,Ahire Deepak¹^ORCID,Basit Abdul¹,Heyward Scott²,Prasad Bhagwat¹^ORCID

Affiliation:

1. College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, Washington 99202, United States

2. BioIVT, Baltimore, Maryland 21227, United States

Funder

Washington State University

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.2c00950

Reference77 articles.

1. Pre-clinical animal models are poor predictors of human toxicities in phase 1 oncology clinical trials

2. Estimating mouse and rat use in American laboratories by extrapolation from Animal Welfare Act-regulated species

3. Applications of Human Pharmacokinetic Prediction in First-in-Human Dose Estimation

4. Utility of Quantitative Proteomics for Enhancing the Predictive Ability of Physiologically Based Pharmacokinetic Models Across Disease States

5. Advancing Predictions of Tissue and Intracellular Drug Concentrations Using In Vitro , Imaging and Physiologically Based Pharmacokinetic Modeling Approaches

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