Developing Translational Vaccines against Heroin and Fentanyl through Investigation of Adjuvants and Stability-Reference-Cited by-同舟云学术

Developing Translational Vaccines against Heroin and Fentanyl through Investigation of Adjuvants and Stability

Published:2020-12-10 Issue:1 Volume:18 Page:228-235
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Blake Steven¹^ORCID,Bremer Paul T.¹²^ORCID,Zhou Bin¹,Petrovsky Nikolai³⁴,Smith Lauren C.¹^ORCID,Hwang Candy S.¹^ORCID,Janda Kim D.¹^ORCID

Affiliation:

1. Department of Chemistry and Immunology, The Skaggs Institute for Chemical Biology, Worm Institute of Research and Medicine (WIRM), The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, United States

2. Cessation Therapeutics, LLC, 3031 Tisch Way, San Jose, California 95128, United States

3. Flinders Medical Centre, Flinders University, GPO Box 2100, Adelaide 5001, South Australia, Australia

4. Vaxine Pty Ltd, 11 Walkley Avenue, Warradale 5046, South Australia, Australia

Funder

National Institute on Drug Abuse

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.0c00837

Reference46 articles.

1. Overdose Death Rates. https://www.drugabuse.gov/related-topics/trends-statistics/overdose-death-rates (accessed June 23, 2020).

2. μ Opioid receptor-mediated G-protein activation by heroin metabolites: evidence for greater efficacy of 6-monoacetylmorphine compared with morphine 11Abbreviations: 6-MAM, 6-monoacetylmorphine; GTPγS, guanosine-5′-O-(γ-thio)-triphosphate; DAMGO, [d-Ala2,(N-Me)Phe4,Gly5(OH)]enkephalin; M-6-G, morphine-6-βd-glucuronide; and hMOR-C6, C6 rat glioma cells expressing human μ opioid receptors.

3. μ-Opioid receptors and regulators of G protein signaling (RGS) proteins: From a symposium on new concepts in mu-opioid pharmacology

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