Molecular Recognition Study toward the Mitochondrial Electron Transport Chain Inhibitor Mubritinib and Human Serum Albumin-Reference-Cited by-同舟云学术

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Molecular Recognition Study toward the Mitochondrial Electron Transport Chain Inhibitor Mubritinib and Human Serum Albumin

Published:2023-06-29 Issue:8 Volume:20 Page:4021-4030
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Menezes Thais Meira¹^ORCID,Seabra Gustavo²^ORCID,Neves Jorge Luiz³^ORCID

Affiliation:

1. Unidade Acadêmica Cabo de Santo Agostinho (UACSA), Universidade Federal Rural de Pernambuco, Recife 54518-430, Brazil

2. Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, Florida 32603, United States

3. Departamento de Química Fundamental (DQF), Universidade Federal de Pernambuco, Recife 50670-901, Brazil

Funder

Funda??o de Amparo ? Ci?ncia e Tecnologia do Estado de Pernambuco

Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico

Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.3c00187

Reference61 articles.

1. Novel HER2 selective tyrosine kinase inhibitor, TAK-165, inhibits bladder, kidney and androgen-independent prostate cancer in vitro and in vivo

2. Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia

3. Mechanistic Investigations of the Mitochondrial Complex I Inhibitor Rotenone in the Context of Pharmacological and Safety Evaluation

4. Mitochondrial function as a therapeutic target in heart failure

5. Mitochondrial complex I as a therapeutic target for Alzheimer's disease

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