Utilizing Laser Activation of Photothermal Plasmonic Nanoparticles to Induce On-Demand Drug Amorphization inside a Tablet-Reference-Cited by-同舟云学术

Utilizing Laser Activation of Photothermal Plasmonic Nanoparticles to Induce On-Demand Drug Amorphization inside a Tablet

Published:2021-05-05 Issue:6 Volume:18 Page:2254-2262
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Hempel Nele-Johanna¹^ORCID,Merkl Padryk²,Asad Shno³,Knopp Matthias Manne⁴,Berthelsen Ragna¹,Bergström Christel A.S.⁵^ORCID,Teleki Alexandra³,Sotiriou Georgios A.²^ORCID,Löbmann Korbinian¹^ORCID

Affiliation:

1. Department of Pharmacy, University of Copenhagen, 2100 Copenhagen, Denmark

2. Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 17177 Stockholm, Sweden

3. Department of Pharmacy, Science for Life Laboratory, Uppsala University, 75123 Uppsala, Sweden

4. Department of Pharmacy, Bioneer:FARMA, 2100 Copenhagen, Denmark

5. Department of Pharmacy, Uppsala University, 75123 Uppsala, Sweden

Funder

Vetenskapsr?det

Det Frie Forskningsr?d

NordForsk

H2020 European Research Council

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.1c00077

Reference51 articles.

1. Polymeric Amorphous Solid Dispersions: A Review of Amorphization, Crystallization, Stabilization, Solid-State Characterization, and Aqueous Solubilization of Biopharmaceutical Classification System Class II Drugs

2. Glass-Transition Temperature of the β-Relaxation as the Major Predictive Parameter for Recrystallization of Neat Amorphous Drugs

3. Downstream processing of polymer-based amorphous solid dispersions to generate tablet formulations

4. Characterization of amorphous solid dispersions: An update

5. Unintended and in situ amorphisation of pharmaceuticals

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