Quantification of Proteins Involved in Drug Metabolism and Disposition in the Human Liver Using Label-Free Global Proteomics-Reference-Cited by-同舟云学术

Quantification of Proteins Involved in Drug Metabolism and Disposition in the Human Liver Using Label-Free Global Proteomics

Published:2019-01-04 Issue:2 Volume:16 Page:632-647
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Couto Narciso¹²^ORCID,Al-Majdoub Zubida M.¹^ORCID,Achour Brahim¹^ORCID,Wright Phillip C.²,Rostami-Hodjegan Amin¹³,Barber Jill¹

Affiliation:

1. Centre for Applied Pharmacokinetic Research, University of Manchester, Stopford Building, Oxford Road, Manchester M13 9PT, U.K.

2. Department of Chemical and Biological Engineering, ChELSI Institute (Chemical Engineering at the Life Science Interface), University of Sheffield, Sir Robert Hadfield Building, Mappin Street, Sheffield S1 3JD, U.K.

3. Simcyp Ltd. (a Certara company), 1 Concourse Way, Sheffield S1 2BJ, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.8b00941

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3. FDA Program of physiologically-based pharmacokinetic and pharmacodynamic modeling (PBPK Program), 2018.

4. Parsing interindividual drug variability: an emerging role for systems pharmacology

5. Simulation and prediction of in vivo drug metabolism in human populations from in vitro data

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