Simulation and prediction of in vivo drug metabolism in human populations from in vitro data
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,General Medicine
Link
http://www.nature.com/articles/nrd2173.pdf
Reference64 articles.
1. Uehling, M.D. Model Patient. Bio-IT World web site [ online ], (2003).
2. Lin, J. H. Sense and nonsense in the prediction of drug–drug interactions. Curr. Drug Metab. 1, 305–331 (2000).
3. Clarke, S. E. & Jeffrey, P. Utility of metabolic stability screening: comparison of in vitro and in vivo clearance. Xenobiotica 31, 591–598 (2001).
4. Andersson, T. B., Bredberg, E., Ericsson, H. & Sjoberg, H. An evaluation of the in vitro metabolism data for predicting the clearance and drug–drug interaction potential of CYP2C9 substrates. Drug Metab. Dispos. 32, 715–721 (2004).
5. Rostami-Hodjegan, A. & Tucker, G. T. 'In silico' simulations to assess the 'in vivo' consequences of 'in vitro' metabolic drug–drug interactions. Drug Discov. Today Technol. 1, 441–448 (2004). A complementary article to this review that places emphasis on issues related to metabolic drug–drug interactions.
Cited by 461 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Inhibition of human UDP-glucuronosyltransferase (UGT) enzymes by darolutamide: prediction of in vivo drug-drug interactions;Chemico-Biological Interactions;2024-09
2. Physiologically based kinetic (PBK) modeling of propiconazole using a machine learning-enhanced read-across approach for interspecies extrapolation;Environment International;2024-07
3. Investigating clinical pharmacokinetics of brivaracetam by using a pharmacokinetic modeling approach;Scientific Reports;2024-06-11
4. Personalized Dosing of Medicines for Children: A Primer on Pediatric Pharmacometrics for Clinicians;Pediatric Drugs;2024-05-16
5. Molecular Cloning, Expression and Enzymatic Characterization of Tetrahymena thermophila Glutathione-S-Transferase Mu 34;The Protein Journal;2024-05-14
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3