1. School of Life Science, Tokyo University of Pharmacy and Life Science, Hachioji, Tokyo 192-0392, Japan, Graduate School of Agricultural and Life Sciences, University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan, Center of Medical Informatics, Dokkyo University School of Medicine, Mibu, Tochigi 321-0293, Japan, Graduate School of Engineering, University of Tokyo, Bunkyo-ku, Tokyo 113-8656, Japan, and Physics Laboratory, Kansai Medical University, Hirakata, Osaka 573-1136, Japan