Synthesis and Antitumor Activity of Methyltriazene Prodrugs Simultaneously Releasing DNA-Methylating Agents and the Antiresistance Drug O6-Benzylguanine-Reference-Cited by-同舟云学术

Synthesis and Antitumor Activity of Methyltriazene Prodrugs Simultaneously Releasing DNA-Methylating Agents and the Antiresistance Drug O6-Benzylguanine

Published:2004-11-23 Issue:27 Volume:47 Page:6875-6883
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Wanner Martin J.¹,Koch Melle¹,Koomen Gerrit-Jan¹

Affiliation:

1. Laboratory of Bioorganic Chemistry, Van't Hoff Institute of Molecular Sciences, University of Amsterdam, Nieuwe Achtergracht 129, NL-1018 WS Amsterdam

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm049556d

Reference34 articles.

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3. Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells

4. Importance of the DNA repair enzyme O6-alkyl guanine alkyltransferase (AT) in cancer chemotherapy

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