Immunogenicity of In Vitro-Transcribed RNA-Reference-Cited by-同舟云学术

Immunogenicity of In Vitro-Transcribed RNA

Published:2021-10-22 Issue:21 Volume:54 Page:4012-4023
ISSN:0001-4842
Container-title:Accounts of Chemical Research
language:en
Short-container-title:Acc. Chem. Res.

Author:

Mu Xin¹²^ORCID,Hur Sun³⁴

Affiliation:

1. School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China

2. Tianjin University and Health-Biotech United Group Joint Laboratory of Innovative Drug Development and Translational Medicine, Tianjin University, Tianjin 300072, China

3. Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, United States

4. Program in Cellular and Molecular Medicine, Boston Children’s Hospital, Boston, Massachusetts 02115, United States

Funder

National Institute of Allergy and Infectious Diseases

State Key Laboratory of Veterinary Etiological Biology

Publisher

American Chemical Society (ACS)

Subject

General Medicine,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.accounts.1c00521

Reference89 articles.

1. Structural Basis for dsRNA Recognition, Filament Formation, and Antiviral Signal Activation by MDA5

2. Molecular Imprinting as a Signal-Activation Mechanism of the Viral RNA Sensor RIG-I

3. Breaching Self-Tolerance to Alu Duplex RNA Underlies MDA5-Mediated Inflammation

4. An origin of the immunogenicity of in vitro transcribed RNA

5. mRNA-based therapeutics — developing a new class of drugs

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