An origin of the immunogenicity of in vitro transcribed RNA-Reference-Cited by-同舟云学术

An origin of the immunogenicity of in vitro transcribed RNA

Published:2018-03-09 Issue:10 Volume:46 Page:5239-5249
ISSN:0305-1048
Container-title:Nucleic Acids Research
language:en
Short-container-title:

Author:

Mu Xin¹²,Greenwald Emily²,Ahmad Sadeem¹²,Hur Sun¹²

Affiliation:

1. Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA

2. Program in Cellular and Molecular Medicine, Boston Children's Hospital, MA 02115, USA

Funder

Cancer Research Institute

Publisher

Oxford University Press (OUP)

Subject

Genetics

Link

http://academic.oup.com/nar/article-pdf/46/10/5239/24962288/gky177.pdf

Reference36 articles.

1. mRNA-based therapeutics—developing a new class of drugs;Sahin;Nat. Rev. Drug Discov.,2014

2. Knocking down disease: a progress report on siRNA therapeutics;Wittrup;Nat. Rev. Genet.,2015

3. Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination;Pardi;Nature,2017

4. Unusual promoter-independent transcription reactions with bacteriophage RNA polymerases;Krupp;Nucleic Acids Res.,1989

5. Self-coded 3′-extension of run-off transcripts produces aberrant products during in vitro transcription with T7 RNA polymerase;Triana-Alonso;J. Biol. Chem.,1995

Cited by 140 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Development and Application of Automated Sandwich ELISA for Quantitating Residual dsRNA in mRNA Vaccines;Vaccines;2024-08-08

2. Comparison of uridine and N1-methylpseudouridine mRNA platforms in development of an Andes virus vaccine;Nature Communications;2024-07-30

3. A new approach to RNA synthesis: immobilization of stably and functionally co-tethered promoter DNA and T7 RNA polymerase;Nucleic Acids Research;2024-07-16

4. Quality by design approach to improve quality and decrease cost of in vitro transcription of mRNA using design of experiments;Biotechnology and Bioengineering;2024-07-16

5. Understanding the impact of in vitro transcription byproducts and contaminants;Frontiers in Molecular Biosciences;2024-07-10