A Pre-Steady State Kinetic Analysis of the αY60W Mutant of trans-3-Chloroacrylic Acid Dehalogenase: Implications for the Mechanism of the Wild-Type Enzyme
Author:
Affiliation:
1. Division of Medicinal Chemistry, College of Pharmacy, ‡Department of Chemistry and Biochemistry, and §Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, Texas 78712, United States
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/bi3010686
Reference41 articles.
1. Bacterial metabolism of 3-chloroacrylic acid
2. Bacterial degradation of 3-chloroacrylic acid and the characterization of cis- and trans-specific dehalogenases
3. Degradation of 1,3-Dichloropropene by Pseudomonas cichorii 170
4. trans -3-Chloroacrylic Acid Dehalogenase from Pseudomonas pavonaceae 170 Shares Structural and Mechanistic Similarities with 4-Oxalocrotonate Tautomerase
5. Reactions of trans-3-Chloroacrylic Acid Dehalogenase with Acetylene Substrates: Consequences of and Evidence for a Hydration Reaction
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