Stereospecific Asymmetric N-Heterocyclic Carbene (NHC)-Catalyzed Redox Synthesis of Trifluoromethyl Dihydropyranones and Mechanistic Insights-Reference-Cited by-同舟云学术

Stereospecific Asymmetric N-Heterocyclic Carbene (NHC)-Catalyzed Redox Synthesis of Trifluoromethyl Dihydropyranones and Mechanistic Insights

Published:2013-09-03 Issue:18 Volume:78 Page:9243-9257
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Davies Alyn T.¹,Taylor James E.¹,Douglas James¹,Collett Christopher J.¹,Morrill Louis C.¹,Fallan Charlene¹,Slawin Alexandra M. Z.¹,Churchill Gwydion²,Smith Andrew D.¹

Affiliation:

1. EaStCHEM, School of Chemistry, University of St Andrews, North Haugh, St Andrews KY16 9ST, United Kingdom

2. Process Research and Development, AstraZeneca, Macclesfield, Cheshire SK10 2NA, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo401433q

Reference53 articles.

1. Fluorine in medicinal chemistry

2. The Many Roles for Fluorine in Medicinal Chemistry

3. Fluorine in Pharmaceuticals: Looking Beyond Intuition

4. Fluorinated Heterocyclic Compounds

5. Asymmetric Construction of Stereogenic Carbon Centers Featuring a Trifluoromethyl Group from Prochiral Trifluoromethylated Substrates

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