Inhibition of dd-Peptidases by a Specific Trifluoroketone: Crystal Structure of a Complex with the Actinomadura R39 dd-Peptidase
Author:
Affiliation:
1. Department of Chemistry, Wesleyan University, Lawn Avenue, Middletown, Connecticut 06459, United States
2. Centre d’Ingéniere des Protéines, Université de Liège, B-4000 Sart Tilman, Liège, Belgium
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/bi400048s
Reference63 articles.
1. Penicillin: its basic site of action as an inhibitor of a peptide cross-linking reaction in cell wall mucopeptide synthesis.
2. Mechanism of action of penicillins: a proposal based on their structural similarity to acyl-D-alanyl-D-alanine.
3. Conformation of penicillin as a transition-state analog of the substrate of peptidoglycan transpeptidase
4. Functional evolution of the serine β-lactamase active site
Cited by 8 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Transient Formation of Hemiketals from Pentafluoro-gem-diols in the Presence of Alcohols;Journal of Fluorine Chemistry;2023-08
2. Advanced approaches of developing targeted covalent drugs;RSC Medicinal Chemistry;2022
3. 1-Aminovinylphosphonate Esters as Substrates for the Diels-Alder Reaction: First Synthetic and Theoretical Study;European Journal of Organic Chemistry;2019-01-15
4. Synthesis of Trifluoromethyl Ketone Containing Amino Acid Building Blocks for the Preparation of Peptide-Based Histone Deacetylase (HDAC) Inhibitors;Synthesis;2018-08-29
5. Glycosyltransferases and Transpeptidases/Penicillin-Binding Proteins: Valuable Targets for New Antibacterials;Antibiotics;2016-02-17
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3