Development of a Scalable Synthesis of a GPR40 Receptor Agonist-Reference-Cited by-同舟云学术

Development of a Scalable Synthesis of a GPR40 Receptor Agonist

Published:2011-04-13 Issue:3 Volume:15 Page:570-580
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Walker Shawn D.¹,Borths Christopher J.¹,DiVirgilio Evan¹,Huang Liang¹,Liu Pingli¹,Morrison Henry¹,Sugi Kiyoshi¹,Tanaka Masahide¹,Woo Jacqueline C. S.¹,Faul Margaret M.¹

Affiliation:

1. Chemical Process Research and Development, Amgen Inc., Thousand Oaks, California 91320, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op1003055

Reference29 articles.

1. Practical Asymmetric Conjugate Alkynylation of Meldrum’s Acid-Derived Acceptors: Access to Chiral β-Alkynyl Acids

2. Asymmetric syntheses of a GPR40 receptor agonist via diastereoselective and enantioselective conjugate alkynylation

3. Enantioselective Synthesis of a GPR40 Agonist AMG 837 via Catalytic Asymmetric Conjugate Addition of Terminal Alkyne to α,β-Unsaturated Thioamide

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