Multi-Target-Directed Drug Design Strategy: From a Dual Binding Site Acetylcholinesterase Inhibitor to a Trifunctional Compound against Alzheimer’s Disease
Author:
Affiliation:
1. Department of Pharmaceutical Sciences and Department of Organic Chemistry, “A. Mangini”, Alma Mater Studiorum, Bologna University, Via Belmeloro 6, I-40126 Bologna, Italy
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm701225u
Reference34 articles.
1. A Century of Alzheimer's Disease
2. 100 Years and Counting: Prospects for Defeating Alzheimer's Disease
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4. The Cholinergic Hypothesis of Age and Alzheimer's Disease-Related Cognitive Deficits: Recent Challenges and Their Implications for Novel Drug Development
5. Multi-functional drugs for various CNS targets in the treatment of neurodegenerative disorders
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