(2S,1‘S,2‘R,3‘R)-2-(2‘-Carboxy-3‘-hydroxymethylcyclopropyl) Glycine Is a Highly Potent Group 2 and 3 Metabotropic Glutamate Receptor Agonist with Oral Activity-Reference-Cited by-同舟云学术

(2S,1‘S,2‘R,3‘R)-2-(2‘-Carboxy-3‘-hydroxymethylcyclopropyl) Glycine Is a Highly Potent Group 2 and 3 Metabotropic Glutamate Receptor Agonist with Oral Activity

Published:2003-12-09 Issue:2 Volume:47 Page:456-466
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Collado Iván¹,Pedregal Concepción¹,Bueno Ana Belén¹,Marcos Alicia¹,González Rosario¹,Blanco-Urgoiti Jaime¹,Pérez-Castells Javier¹,Schoepp Darryle D.¹,Wright Rebecca A.¹,Johnson Bryan G.¹,Kingston Ann E.¹,Moher Eric D.¹,Hoard David W.¹,Griffey Kelly I.¹,Tizzano Joseph P.¹

Affiliation:

1. Lilly, SA, Avda. de la Industria 30, 28108 Alcobendas, Madrid, Spain, Facultad de Ciencias Experimentales y de la Salud, Universidad San PabloCEU, Urb. Montepríncipe, 28668 Boadilla del Monte, Madrid, Spain, and Lilly Research Laboratories, Indianapolis, Indiana 46285

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm030967o

Reference77 articles.

1. Excitatory amino acid receptors: A gallery of new targets for pharmacological intervention

2. Cloned Glutamate Receptors

3. Molecular Diversity and Functions of Glutamate Receptors

4. Molecular tinkering of G protein-coupled receptors: an evolutionary success

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