Structure−Activity Relationships in a Series of Bisquaternary Bisphthalimidine Derivatives Modulating the Muscarinic M2-Receptor Allosterically-Reference-Cited by-同舟云学术

Structure−Activity Relationships in a Series of Bisquaternary Bisphthalimidine Derivatives Modulating the Muscarinic M2-Receptor Allosterically

Published:2000-05-16 Issue:11 Volume:43 Page:2155-2164
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Botero Cid Hector M.¹,Tränkle Christian¹,Baumann Knut¹,Pick Rainer¹,Mies-Klomfass Elisabeth¹,Kostenis Evi¹,Mohr Klaus¹,Holzgrabe Ulrike¹

Affiliation:

1. Pharmaceutical Chemistry, Institute of Pharmacy, University of Würzburg, Am Hubland, 97074 Würzburg, FRG, and Pharmacology and Toxicology, Institute of Pharmacy, University of Bonn, An der Immenburg 4, 53121 Bonn, FRG

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm991136e

Reference33 articles.

1. Allosteric modulators of ligand binding to muscarinic acetylcholine receptors

2. ALLOSTERIC INTERACTIONS AT MUSCARINIC CHOLINOCEPTORS

3. Divergent Modes of Action among Cationic Allosteric Modulators of Muscarinic M2 Receptors

4. Identification of a [3H]Ligand for the Common Allosteric Site of Muscarinic Acetylcholine M2 Receptors

Cited by 81 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. High stereoselectivity synthesis of Z-3-methyleneisoindolin-1-ones on a Cu/ETS-10 catalyst via domino coupling–cyclization without the use of protective groups and ligands;New Journal of Chemistry;2024

2. A rhodium-catalyzed cascade C–H activation/annulation strategy for the expeditious assembly of pyrrolidinedione-fused 1,2-benzothiazines;Organic & Biomolecular Chemistry;2024

3. Cobalt‐Catalyzed, 2‐Aminopyridine‐N‐Oxide‐Directed C(sp²)−H Bond Functionalization with Maleimides: Facile Access to Isoindolone Spirosuccinimides;European Journal of Organic Chemistry;2023-08-02

4. Synthesis of Heterocycles from 2‐Acylbenzoic Acids;European Journal of Organic Chemistry;2023-06-20

5. Rh(III)-Catalyzed [4+1] Annulation of Sulfoximines with Maleimides: Access to Benzoisothiazole Spiropyrrolidinediones;J ORG CHEM;2023