Model-Based Scale-up and Design Space Determination for a Batch Reactive Distillation with a Dean–Stark Trap
Author:
Affiliation:
1. Small Molecule Design and Development, Eli Lilly & Co., Lilly Corporate Center, Indianapolis, Indiana 46285, United States
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/op4001127
Reference28 articles.
1. Reactive Distillation Design and Control
2. Modelling reactive distillation
3. Experimental model validation for n-propyl propionate synthesis in a reactive distillation column coupled with a liquid–liquid phase separator
4. International Conference on Harmonisation (ICH). Guideline Q8 (R2): Note For Guidance On Pharmaceutical Development, 2009; http://www.ich.org/products/guidelines/quality/article/quality-guidelines.html(accessed July 11, 2013) .
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