Systematic Exploration of Dual-Acting Modulators from a Combined Medicinal Chemistry and Biology Perspective-Reference-Cited by-同舟云学术

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Systematic Exploration of Dual-Acting Modulators from a Combined Medicinal Chemistry and Biology Perspective

Published:2013-01-29 Issue:3 Volume:56 Page:1197-1210
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bornot Aurelie¹,Bauer Udo²,Brown Alastair³,Firth Mike¹,Hellawell Caroline¹,Engkvist Ola⁴

Affiliation:

1. Discovery Sciences, Computational Biology, AstraZeneca R&D, Alderley Park, Macclesfield, Cheshire, SK10 4TG, U.K.

2. iMED CV/GI, Medicinal Chemistry, AstraZeneca R&D, Pepparedsleden 1, Mölndal, SE-431 83, Sweden

3. iMED CV/GI, AstraZeneca R&D, Alderley Park, Macclesfield, Cheshire, SK10 4TG, U.K.

4. Discovery Sciences, Computational Chemistry, AstraZeneca R&D, Pepparedsleden 1, Mölndal, SE-431 83, Sweden

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm301653f

Reference62 articles.

1. The cost of drug development: A systematic review

2. Network pharmacology: the next paradigm in drug discovery

3. DrugBank: a knowledgebase for drugs, drug actions and drug targets

4. Drug—target network

5. Data completeness—the Achilles heel of drug-target networks

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