p-Trifluoromethyldiazirinyl-etomidate: A Potent Photoreactive General Anesthetic Derivative of Etomidate That Is Selective for Ligand-Gated Cationic Ion Channels-Reference-Cited by-同舟云学术

p-Trifluoromethyldiazirinyl-etomidate: A Potent Photoreactive General Anesthetic Derivative of Etomidate That Is Selective for Ligand-Gated Cationic Ion Channels

Published:2010-08-12 Issue:17 Volume:53 Page:6432-6444
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Husain S. Shaukat¹,Stewart Deirdre¹,Desai Rooma¹,Hamouda Ayman K.²,Li S. Guo-Dong³,Kelly Elizabeth¹,Dostalova Zuzana¹,Zhou Xiaojuan¹,Cotten Joseph F.¹,Raines Douglas E.¹,Olsen Richard W.³,Cohen Jonathan B.²,Forman Stuart A.¹,Miller Keith W.¹⁴

Affiliation:

1. Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, 32 Fruit Street, Boston, Massachusetts 02114

2. Department of Neurobiology

3. Department of Molecular and Medical Pharmacology, Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California 90095

4. Department of Biological Chemistry and Molecular Pharmacology

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm100498u

Reference40 articles.

1. DL-1-(1-Arylalkyl)imidazole-5-carboxylate Esters. A Novel Type of Hypnotic Agents

2. Stereoselective Effects of Etomidate Optical Isomers on Gamma-aminobutyric Acid Type A Receptors and Animals

3. The GABA_A Receptor: An Important Locus for Intravenous Anaesthetic Action

4. Anaesthetic modulation of nicotinic ion channel kinetics in bovine chromaffin cells

5. 2-(3-Methyl-3H-diaziren-3-yl)ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate: A Derivative of the Stereoselective General Anesthetic Etomidate for Photolabeling Ligand-Gated Ion Channels

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