1. Institute of Human Genetics, Charité, University Medicine Berlin, Augustenbuger Platz 1, 13353 Berlin, Germany, Department of Pediatric Neurology, Charité, University Medicine Berlin, Augustenbuger Platz 1, 13353 Berlin, Germany, Institute of Medical Genetics, Charité, University Medicine Berlin, Augustenbuger Platz 1, 13353 Berlin, Germany, and Center for Molecular Neurobiology, University of Hamburg, Martinistrasse 52, 20246 Hamburg, Germany