Discovery of Highly Potent and Selective Biphenylacylsulfonamide-Based β3-Adrenergic Receptor Agonists and Evaluation of Physical Properties as Potential Overactive Bladder Therapies: Part 5
Author:
Affiliation:
1. Chemistry Research Laboratories, Pharmacology Research Laboratories, Applied Pharmacology Research Laboratories, and Analysis & Pharmacokinetic Research Laboratories, Astellas Pharma Inc., 21, Miyukigaoka, Tsukuba-shi, Ibaraki 305-8585, Japan
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm9000709
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1. The standardisation of terminology of lower urinary tract function: Report from the standardisation sub-committee of the International Continence Society
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1. Discovery of Novel Indazole Derivatives as Orally Available β3-Adrenergic Receptor Agonists Lacking Off-Target-Based Cardiovascular Side Effects;Journal of Medicinal Chemistry;2017-04-11
2. β 3 -AR Agonists for the Treatment of Overactive Bladder;Comprehensive Medicinal Chemistry III;2017
3. Discovery of benzamides as potent human β3 adrenergic receptor agonists;Bioorganic & Medicinal Chemistry Letters;2016-01
4. Discovery of Novel Indazole Derivatives as Highly Potent and Selective Human β3-Adrenergic Receptor Agonists with the Possibility of Having No Cardiovascular Side Effects;Journal of Medicinal Chemistry;2015-07-15
5. Design, Synthesis, and Evaluation of Conformationally Restricted Acetanilides as Potent and Selective β3Adrenergic Receptor Agonists for the Treatment of Overactive Bladder;Journal of Medicinal Chemistry;2014-02-05
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