Process Development of a Scaleable Route to (2R)-[3-(2-Aminopropyl)-1H-indol-7-yloxy]-N,N-diethylacetamide: A Key Intermediate for AJ-9677, a Potent and Selective Human and Rat β3-Adrenergic Receptor Agonist-Reference-Cited by-同舟云学术

Process Development of a Scaleable Route to (2R)-[3-(2-Aminopropyl)-1H-indol-7-yloxy]-N,N-diethylacetamide: A Key Intermediate for AJ-9677, a Potent and Selective Human and Rat β3-Adrenergic Receptor Agonist

Published:2004-02-12 Issue:2 Volume:8 Page:238-245
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Harada Hiroshi¹,Fujii Akihito¹,Odai Osamu¹,Kato Shiro¹

Affiliation:

1. Chemistry Research Laboratories, Dainippon Pharmaceutical Co., Ltd., Enoki 33-94, Suita, Osaka 564-0053, Japan

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op0341869

Reference19 articles.

1. Atypical β-adrenoceptor on brown adipocytes as target for anti-obesity drugs

2. Pharmacological Treatment of Obesity: Therapeutic Strategies

3. β3-adrenergic agonists: potential therapeutics for obesity

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