N,N-Diethyl-(R)-[3-(2-aminopropyl)-1H-indol-7-yloxy]acetamide: Its Process Chemistry Ranging from Enantiocontrolled Construction of the Chiral Amine Side Chain to Regioselective Functionalization of the Aromatic Starting Materials-Reference-Cited by-同舟云学术

N,N-Diethyl-(R)-[3-(2-aminopropyl)-1H-indol-7-yloxy]acetamide: Its Process Chemistry Ranging from Enantiocontrolled Construction of the Chiral Amine Side Chain to Regioselective Functionalization of the Aromatic Starting Materials

Published:2006-12-20 Issue:1 Volume:11 Page:73-80
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Ikunaka Masaya¹,Kato Shiro¹,Sugimori Daisuke¹,Yamada Yasuhiro¹

Affiliation:

1. Research & Development Center, Nagase & Co., Ltd. 2-2-3 Murotani, Nishi-ku, Kobe, Hyogo 651-2241, Japan, Faculty of Symbiotic Systems Science, Fukushima University, 1 Kanayagawa, Fukushima, Fukushima 960-1296, Japan, Medicinal Chemistry Group I, Chemistry Research Laboratories, Dainippon Sumitomo Pharma Co., Ltd., Enoki 33-94, Suita, Osaka 564-0053, Japan, Department of Applied Biological Science, Faculty of Life Science, Fukuyama University, 1 Sanzo, Gakuen-cho, Fukuyama, Hiroshima 729-0292, Japan

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op060210h

Reference30 articles.

1. WEIGHING IN ON OBESITY

2. Novel and potent human and rat β3-Adrenergic receptor agonists containing substituted 3-indolylalkylamines

3. METABOLIC SYNDROME

4. Process Development of a Scaleable Route to (2R)-[3-(2-Aminopropyl)-1H-indol-7-yloxy]-N,N-diethylacetamide: A Key Intermediate for AJ-9677, a Potent and Selective Human and Rat β3-Adrenergic Receptor Agonist

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