Asymmetric 1,3-Dipolar Cycloaddition of a (Z)-Alkene Dipolarophile. Synthesis of (3S,4R) Ethyl 1-Azabicyclo[2.2.1]heptane-3-carboxylate
Author:
Affiliation:
1. Synthetic Chemistry, GlaxoSmithKline Pharmaceuticals, Old Powder Mills, Nr. Leigh, Tonbridge, Kent, TN11 9AN. UK John_S_Carey@sbphrd.com
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/jo001797f
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5. Design of [R-(Z)]-(+)-α-(Methoxyimino)-1-azabicyclo[2.2.2]octane-3-acetonitrile (SB 202026), a Functionally Selective Azabicyclic Muscarinic M1 Agonist Incorporating the N-Methoxy Imidoyl Nitrile Group as a Novel Ester Bioisostere
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