Development of an Outward Proton Pumping Rhodopsin with a New Record in Thermostability by Means of Amino Acid Mutations

Author:

Yasuda Satoshi12ORCID,Akiyama Tomoki1,Kojima Keiichi3,Ueta Tetsuya3,Hayashi Tomohiko45,Ogasawara Satoshi12,Nagatoishi Satoru6ORCID,Tsumoto Kouhei67ORCID,Kunishima Naoki8,Sudo Yuki3ORCID,Kinoshita Masahiro125ORCID,Murata Takeshi12

Affiliation:

1. Graduate School of Science, Chiba University, 1-33 Yayoi-cho, Inage, Chiba 263-8522, Japan

2. Membrane Protein Research and Molecular Chirality Research Centers, Chiba University, 1-33 Yayoi-cho, Inage, Chiba 263-8522, Japan

3. Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University, Okayama 700-8530, Japan

4. Interdisciplinary Program of Biomedical Engineering, Assistive Technology, and Art and Sports Sciences, Faculty of Engineering, Niigata University, 8050 Ikarashi 2-no-cho, Nishi-ku, Niigata 950-2181, Japan

5. Institute of Advanced Energy, Kyoto University, Uji, Kyoto 611-0011, Japan

6. The Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-ku, Tokyo 108-8639, Japan

7. Department of Bioengineering, School of Engineering, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-8656, Japan

8. RIKEN RSC-Rigaku Collaboration Center, RIKEN SPring-8 Center, Sayo-gun, Hyogo 679-5165, Japan

Funder

Japan Agency for Medical Research and Development

Japan Society for the Promotion of Science

Council for Science, Technology and Innovation

Publisher

American Chemical Society (ACS)

Subject

Materials Chemistry,Surfaces, Coatings and Films,Physical and Theoretical Chemistry

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