Predicting a Drug’s Membrane Permeability: A Computational Model Validated With in Vitro Permeability Assay Data-Reference-Cited by-同舟云学术

Predicting a Drug’s Membrane Permeability: A Computational Model Validated With in Vitro Permeability Assay Data

Published:2017-05-12 Issue:20 Volume:121 Page:5228-5237
ISSN:1520-6106
Container-title:The Journal of Physical Chemistry B
language:en
Short-container-title:J. Phys. Chem. B

Author:

Bennion Brian J.¹,Be Nicholas A.¹,McNerney M. Windy¹²,Lao Victoria¹,Carlson Emma M.³,Valdez Carlos A.⁴,Malfatti Michael A.¹,Enright Heather A.¹,Nguyen Tuan H.⁵,Lightstone Felice C.¹,Carpenter Timothy S.¹^ORCID

Affiliation:

1. Biosciences and Biotechnology Division, Lawrence Livermore National Laboratory, Livermore, California 94550, United States

2. War Related Illness and Injury Study Center, Veterans Affairs, Palo Alto, California 94304, United States

3. U.S. Naval Academy, Annapolis, Maryland 21402, United States

4. Nuclear and Chemical Sciences Division, Lawrence Livermore National Laboratory, Livermore, California 94550, United States

5. Global Security Directorate, Lawrence Livermore National Laboratory, Livermore, California 94550, United States

Funder

Defense Threat Reduction Agency

Publisher

American Chemical Society (ACS)

Subject

Materials Chemistry,Surfaces, Coatings and Films,Physical and Theoretical Chemistry

Link

http://pubs.acs.org/doi/pdf/10.1021/acs.jpcb.7b02914

Reference65 articles.

1. Drug interactions with lipid membranes

2. Diffusion of Macromolecules in the Brain: Implications for Drug Delivery

3. Characteristics of compounds that cross the blood-brain barrier

4. Physicochemical High Throughput Screening: Parallel Artificial Membrane Permeation Assay in the Description of Passive Absorption Processes

5. High throughput artificial membrane permeability assay for blood–brain barrier

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