Rational Design of Macrolides by Virtual Screening of Combinatorial Libraries Generated through in Silico Manipulation of Polyketide Synthases
Author:
Affiliation:
1. Department of Biotechnology, Norwegian University of Science and Technology, Trondheim, Norway and Institute of Biomedical Chemistry of Russian Academy of Medical Science, Moscow, Russia
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm051035i
Reference66 articles.
1. The evolving role of natural products in drug discovery
2. Libraries from natural product-like scaffolds
3. Pure compound libraries; a new perspective for natural product based drug discovery
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