Discovery of P2Y2 Receptor Antagonist Scaffolds through Virtual High-Throughput Screening
Author:
Affiliation:
1. PharmaCenter Bonn, Pharmaceutical Institute, Pharmaceutical Sciences Bonn (PSB), Pharmaceutical & Medicinal Chemistry, University of Bonn, 53121 Bonn, Germany
2. Research Training Group 1873, University of Bonn, 53127 Bonn, Germany
Funder
Bundesministerium f?r Bildung und Forschung
Deutscher Akademischer Austauschdienst
Deutsche Forschungsgemeinschaft
Publisher
American Chemical Society (ACS)
Subject
Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jcim.1c01235
Reference54 articles.
1. G Protein-Coupled Receptors as Targets for Approved Drugs: How Many Targets and How Many Drugs?
2. Ligand binding and activation of UTP-activated G protein-coupled P2Y2 and P2Y4 receptors elucidated by mutagenesis, pharmacological and computational studies
3. Key Determinants of Nucleotide-Activated G Protein-Coupled P2Y2 Receptor Function Revealed by Chemical and Pharmacological Experiments, Mutagenesis and Homology Modeling
4. Structure activity and molecular modeling analyses of ribose- and base-modified uridine 5′-triphosphate analogues at the human P2Y2 and P2Y4 receptors
Cited by 6 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. PDZ Peptide of the ZO-1 Protein Significantly Increases UTP-Induced MUC8 Anti-Inflammatory Mucin Overproduction in Human Airway Epithelial Cells;Molecules and Cells;2023-11
2. The bumpy road of purinergic inhibitors to clinical application in immune-mediated diseases;Neural Regeneration Research;2023-10-02
3. New paradigms in purinergic receptor ligand discovery;Neuropharmacology;2023-06
4. Purinergic GPCR-integrin interactions drive pancreatic cancer cell invasion;eLife;2023-03-21
5. Extracellular ATP drives pancreatic cancer cell invasion via purinergic receptor-integrin interactions;2022-10-24
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3