Theoretical Investigation of the Structural Characteristics in the Active State of Akt1 Kinase
Author:
Affiliation:
1. State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, China
Funder
Shanghai Jiao Tong University
Ministry of Science and Technology of the People's Republic of China
National Natural Science Foundation of China
Publisher
American Chemical Society (ACS)
Subject
Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jcim.8b00506
Reference49 articles.
1. Conformational sampling of membranes by Akt controls its activation and inactivation
2. PI3K/AKT signaling pathway and cancer: an updated review
3. The Prognostic Significance of Phosphatidylinositol 3-Kinase Pathway Activation in Human Gliomas
4. AKT and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor cell growth
5. Akt kinases in breast cancer and the results of adjuvant therapy
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