Comparative Dynamics and Functional Mechanisms of the CYP17A1 Tunnels Regulated by Ligand Binding-Reference-Cited by-同舟云学术

Comparative Dynamics and Functional Mechanisms of the CYP17A1 Tunnels Regulated by Ligand Binding

Published:2020-06-12 Issue:7 Volume:60 Page:3632-3647
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

Xiao Fei¹,Song Xingyu¹,Tian Peiyi¹,Gan Mi¹,Verkhivker Gennady M.²³^ORCID,Hu Guang¹^ORCID

Affiliation:

1. Center for Systems Biology, Department of Bioinformatics, School of Biology and Basic Medical Sciences, Soochow University, Suzhou 215123, China

2. Department of Computational and Data Sciences, Chapman University, One University Drive, Orange, California 92866, United States

3. Department of Biomedical and Pharmaceutical Sciences, Chapman University Pharmacy School, 9401 Jeronimo Rd, Irvine, California 92618, United States

Funder

China Postdoctoral Science Foundation

Government of Jiangsu Province

National Natural Science Foundation of China

Priority Academic Program Development of Jiangsu Higher Education Institutions

Publisher

American Chemical Society (ACS)

Subject

Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jcim.0c00447

Reference79 articles.

1. Basic Review of the Cytochrome P450 System

2. Human cytochrome P450 enzymes 5–51 as targets of drugs and natural and environmental compounds: mechanisms, induction, and inhibition – toxic effects and benefits

3. The Cytochrome P450 Superfamily: Biochemistry, Evolution and Drug Metabolism in Humans

4. Mechanisms of Cytochrome P450-Catalyzed Oxidations

5. Automated Information Extraction and Structure−Activity Relationship Analysis of Cytochrome P450 Substrates

Cited by 16 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Assessing the role of residue Phe108 of cytochrome P450 3A4 in allosteric effects of midazolam metabolism;Physical Chemistry Chemical Physics;2024

2. Applications of graph theory in studying protein structure, dynamics, and interactions;Journal of Mathematical Chemistry;2023-09-04

3. Elastic network models and molecular dynamic simulations reveal the molecular basis of allosteric regulation in ubiquitin-specific protease 7 (USP7);Computers in Biology and Medicine;2023-08

4. Non-steroidal CYP17A1 Inhibitors: Discovery and Assessment;Journal of Medicinal Chemistry;2023-05-16

5. Key regulators in the architecture of substrate access/egress channels in mammalian cytochromes P450 governing flexibility in substrate oxyfunctionalization;Journal of Inorganic Biochemistry;2023-04