Computational Study Reveals the Role of Water Molecules in the Inhibition Mechanism of LAT1 by 1,2,3-Dithiazoles
Author:
Affiliation:
1. Department of Chemistry and Chemical Technologies, University of Calabria, 87036 Arcavacata di Rende, Cosenza, Italy
Funder
Dipartimento di Chimica, Universit?? della Calabria
Publisher
American Chemical Society (ACS)
Subject
Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jcim.1c01012
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1. Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc
2. Amino acid homeostasis and signalling in mammalian cells and organisms
3. Structure of the human LAT1–4F2hc heteromeric amino acid transporter complex
4. Expression Cloning and Characterization of a Transporter for Large Neutral Amino Acids Activated by the Heavy Chain of 4F2 Antigen (CD98)
5. Pharmacokinetic role of L-type amino acid transporters LAT1 and LAT2
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