A Nonhydrolyzable Reactive cAMP Analogue, (Sp)-8-[(4-Bromo-2,3-dioxobutyl)thio]adenosine 3‘,5‘-Cyclic S-(Methyl)monophosphorothioate, Irreversibly Inactivates Human Platelet cGMP-Inhibited cAMP Phosphodiesterase at Micromolar Concentrations
Author:
Affiliation:
1. Thrombosis Research Center, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, and Department of Chemistry and Biochemistry, University of Delaware, Newark, Delaware 19716
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/bi0119823
Reference28 articles.
1. Thiols Protect the Inhibition of Myocardial Aconitase by Peroxynitrite
Cited by 4 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. A new nonhydrolyzable reactive cGMP analogue, (Rp)-guanosine-3′,5′-cyclic-S-(4-bromo-2,3-dioxobutyl)monophosphorothioate, which targets the cGMP binding site of human platelet PDE3A;Bioorganic Chemistry;2008-06
2. New Insights from the Structure-Function Analysis of the Catalytic Region of Human Platelet Phosphodiesterase 3A;Journal of Biological Chemistry;2006-09
3. Insights from Affinity Labeling into Nucleotide- and Coenzyme-Dependent Enzyme Catalysis and Regulation;Letters in Drug Design & Discovery;2006-09-01
4. Platelet Cyclic Adenosine Monophosphate Phosphodiesterases: Targets for Regulating Platelet-Related Thrombosis;Seminars in Thrombosis and Hemostasis;2004-08
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