Stereoselective Syntheses of the Antihistaminic Drug Olopatadine and Its E-Isomer-Reference-Cited by-同舟云学术

Stereoselective Syntheses of the Antihistaminic Drug Olopatadine and Its E-Isomer

Published:2012-07-05 Issue:14 Volume:77 Page:6340-6344
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Bosch Joan¹,Bachs Jordi²,Gómez Antonia M.¹,Griera Rosa¹,Écija Marta¹,Amat Mercedes¹

Affiliation:

1. Laboratory of Organic Chemistry, Faculty of Pharmacy, and Institute of Biomedicine (IBUB), University of Barcelona, Av. Joan XXIII s/n, 08028 Barcelona, Spain

2. Urquima, S.A., Arnau de Vilanova 22-42, 08105 Sant Fost de Campsentelles, Barcelona, Spain

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo300925c

Reference20 articles.

1. The In Vitro and In Vivo Ocular Pharmacology of Olopatadine (AL-4943A), an Effective Anti-Allergic/Antihistaminic Agent

2. Synthesis and antiallergic activity of 11-(aminoalkylidene)-6,11-dihydrodibenz[b,e]oxepin derivatives

3. A New Efficient Synthetic Route for the Synthesis of the Antiallergic Drug, Olopatadine Hydrochloride, via Stereospecific Palladium-Catalyzed Reaction

4. Bosch, J.; Bachs, J.; Gómez, A.; Alonso, Y.; Bessa, M.PCT Int. Appl. WO/2006/010459 A1.

5. The Wittig olefination reaction and modifications involving phosphoryl-stabilized carbanions. Stereochemistry, mechanism, and selected synthetic aspects

Cited by 14 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Molecular modeling and solubility of olopatadine hydrochloride polymorphs;Computational and Theoretical Chemistry;2023-06

2. The Mizoroki–Heck reaction between in situ generated alkenes and aryl halides: cross-coupling route to substituted olefins;RSC Advances;2023

3. Exciting progress in the transition metal‐catalyzed synthesis of oxepines, benzoxepines, dibenzoxepines, and other derivatives;Applied Organometallic Chemistry;2021-12-28

4. Olefination, Metathesis, and Epoxidation Reactions;Applied Organic Chemistry;2020-12-11

5. Novel and Efficient Synthesis of Deuterium-Labeled Olopatadine-d6;Russian Journal of Organic Chemistry;2019-09