Chemo-Enzymatic Strategy for the Efficient Synthesis of Steroidal Drugs with 10α-Methyl Group and a Side Chain at C17-Position from Biorenewable Phytosterols-Reference-Cited by-同舟云学术

Chemo-Enzymatic Strategy for the Efficient Synthesis of Steroidal Drugs with 10α-Methyl Group and a Side Chain at C17-Position from Biorenewable Phytosterols

Published:2024-03-29 Issue:4 Volume:4 Page:1356-1364
ISSN:2691-3704
Container-title:JACS Au
language:en
Short-container-title:JACS Au

Author:

Li Xuemei¹,Zhang Rui¹,Li Jianjiong¹,Liu Na¹,Chen Xi¹^ORCID,Liu Yiyin¹,Zhao Gang²^ORCID,Ding Kai²,Yao Peiyuan¹^ORCID,Feng Jinhui¹^ORCID,Wu Qiaqing¹^ORCID,Zhu Dunming¹^ORCID,Ma Yanhe¹

Affiliation:

1. National Engineering Research Center of Industrial Enzymes and Tianjin Engineering Research Center of Biocatalytic Technology, Key Laboratory of Engineering Biology for Low-carbon Manufacturing, National Center of Technology Innovation for Synthetic Biology, and Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China

2. CAS Key Laboratory of Synthetic Chemistry of Natural Substances, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/jacsau.3c00688

Reference32 articles.

1. https://njardarson.lab.arizona.edu/content/top-pharmaceuticals-poster (accessed on September 10, 2023). Also see: McGrath, N. A.; Brichacek, M.; Njardarson J. T. A Graphical Journey of Innovative Organic Architectures That Have Improved Our Lives. J. Chem. Edu. 2010, 87, 1348-1349.

2. Microbial Degradation of Steroids to Hexahydroindanone Derivatives

3. Synthesis of labelled [13C6]testosterone and [13C5]19-nortestosterone

4. Studies on Chromium(0)-Promoted Higher-Order Cycloaddition-Based Benzannulation. Total Synthesis of (+)-Estradiol

5. Efficient microbial synthesis of key steroidal intermediates from bio-renewable phytosterols by genetically modified Mycobacterium fortuitum strains

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