Structural, Kinetic, and Pharmacodynamic Mechanisms of d-Amino Acid Oxidase Inhibition by Small Molecules-Reference-Cited by-同舟云学术

Structural, Kinetic, and Pharmacodynamic Mechanisms of d-Amino Acid Oxidase Inhibition by Small Molecules

Published:2013-04-30 Issue:9 Volume:56 Page:3710-3724
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hopkins Seth C.¹,Heffernan Michele L. R.¹,Saraswat Lakshmi D.¹,Bowen Carrie A.¹,Melnick Laurence¹,Hardy Larry W.¹,Orsini Michael A.¹,Allen Michael S.²,Koch Patrick¹,Spear Kerry L.¹,Foglesong Robert J.³,Soukri Mustapha³,Chytil Milan¹,Fang Q. Kevin¹,Jones Steven W.¹,Varney Mark A.¹,Panatier Aude⁴,Oliet Stephane H. R.⁴,Pollegioni Loredano⁵⁶,Piubelli Luciano⁵⁶,Molla Gianluca⁵⁶,Nardini Marco⁷,Large Thomas H.¹

Affiliation:

1. Sunovion Pharmaceuticals Inc., Marlborough, Massachusetts 01752, United States

2. Tandem Labs, Durham, North Carolina, United States

3. Scynexis, Durham, North Carolina, United States

4. Neurocentre Magendie, Inserm U862 and Université de Bordeaux, Bordeaux, F-33077, France

5. Dipartimento di Biotecnologie e Scienze della Vita, Università degli Studi dell’Insubria, Via J. H. Dunant 3, 21100 Varese, Italy

6. The Protein Factory, Politecnico di Milano, ICRM-CNR and Università degli Studi dell’Insubria, Via Mancinelli 7, 20131 Milano, Italy

7. Department of Biosciences, University of Milan, I-20133 Milano, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm4002583

Reference67 articles.

1. The NMDA receptor as a target for cognitive enhancement

2. NMDA receptors and metaplasticity: Mechanisms and possible roles in neuropsychiatric disorders

3. Basic Pharmacology of NMDA Receptors

4. Endogenous d-Serine Contributes to NMDA-Receptor–Mediated Light-Evoked Responses in the Vertebrate Retina

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