NMR-Based Screening with Competition Water−Ligand Observed via Gradient Spectroscopy Experiments: Detection of High-Affinity Ligands
Author:
Affiliation:
1. Department of Chemistry, Pharmacia, Viale Pasteur 10, 20014 Nerviano (MI), Italy
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm011122k
Reference32 articles.
1. Discovering High-Affinity Ligands for Proteins: SAR by NMR
2. NMR spectroscopy as a tool for structure-based drug design
3. NMR screening in drug discovery
4. The SHAPES strategy: an NMR-based approach for lead generation in drug discovery
5. NMR-based screening in drug discovery
Cited by 116 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Affinity measurement of strong ligands with NMR spectroscopy: Limitations and ways to overcome them;Progress in Nuclear Magnetic Resonance Spectroscopy;2023-11
2. Review on NMR as a tool to analyse natural products extract directly: Molecular structure elucidation and biological activity analysis;Phytochemical Analysis;2023-10-03
3. Studying the interaction of glycans with intact virions and virus‐like particles by ligand‐observed NMR spectroscopy;Magnetic Resonance in Chemistry;2023-09-30
4. Emerging Direct Targeting β-Catenin Agents;Molecules;2022-11-10
5. NMR-based Ligand–Receptor Interaction Studies under Conventional and Unconventional Conditions;NMR Spectroscopy for Probing Functional Dynamics at Biological Interfaces;2022-08-17
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3